43780
Fluka
Dimethyl 3,3′-dithiopropionimidate dihydrochloride
BioChemika, purum, ≥95.0% (AT)
| Synonym: | Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride, DTBP, Wang/Richards’ reagent |
| CAS Number: | 38285-78-8 |
| Linear Formula: | C8H16N2O2S2 · 2HCl |
| Molecular Weight: | 309.28 |
| MDL number: | MFCD00043245 |
| PubChem Substance ID: | 24867398 |
Description
| Analysis Note | product decomposes at 111-115°C, residual melts at 160-164°C |
| Application | A homobifunctional, cleavable cross-linking reagent. Typically, reacted with primary amines in the pH range 7.0-10.0 to form amidine bonds. |
| Caution | The reagant is readily hydrolyzed at neutral pH. Avoid use of reducing agents during coupling reactions. |
| Other Notes | Cleavable bifunctional reagent used for cross-linking of membrane proteins and hemoglobin1; For the preparation of an activated solid support2; Cross-linking of a cytochrome oxidase complex3 |
| Note that the amidine linkage preserves original primary amine positive charge. The disulfide linkage is cleavable by mild reduction. Incorporates an eight atom linker. |
Properties
| product line | BioChemika |
| grade | purum |
| assay | ≥95.0% (AT) |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 38 |
| Safety Statements | 36 |
| WGK Germany | 3 |
Related Products
| Replaced by | D2388, Dimethyl 3,3′-dithiopropionimidate dihydrochloride |
